Ketogenic Diets: A Gut-Brain Connection Revealed in Neurological Health
A new study unveils how dietary changes impact gut microbiota and neurological outcomes
In a recent study, scientists have explored the link between Ketogenic Diets and changes in gut microbiota, shedding light on a potential mechanism for the improvement of ‘neurological’ diseases that affect the brain, spinal cord, or nerves (e.g., Alzheimer's, Parkinson's, epilepsy, multiple sclerosis, and migraine).
What is the Ketogenic Diet?
A ketogenic diet is a low-carbohydrate, high-fat eating plan designed to induce ketosis, a metabolic state where the body burns fat for fuel. Typically, it restricts carbohydrate intake to around 5-10% of total daily calories, focusing on fats and moderate protein
And Gut Microbiota?
Gut microbiota refers to the diverse community of trillions of microorganisms, including bacteria, viruses, fungi, and archaea, residing in the digestive tract; they play an important role in digestion, metabolism, and immune function. Imbalances in gut microbiota have been linked to various health conditions, influencing overall well-being.
Back to the Study
Researchers examined 13 trials, which investigated the impact of the ketogenic diet on the gut microbiota in neurological disease patients. The findings are promising, indicating that the ketogenic diet not only enhances clinical outcomes by reducing disease severity and recurrence rates but also induces significant alterations in microbiota composition.
The identified changes include an increase in the abundance of specific microbiota like Escherichia, Bacteroides, and Faecalibacterium, along with a reduction in others such as Eubacterium and Akkermansia. Moreover, shifts in the concentrations of various neurological health markers were observed (e.g., faecal short-chain fatty acids and branched-chain fatty acids, beta Hydroxybutyrate, trimethylamine N-oxide, and N-acetylserotonin levels).
These findings suggest a compelling connection between the ketogenic diet, gut microbiota, and neurological health. The study emphasizes the need for further research to fully understand and harness the potential of dietary interventions in promoting neurological well-being.
Source: https://doi.org/10.1186/s12937-023-00893-2